Factors That Cause Diabetes

Stochastic Mutations in Mitochondrial DNA are Commonplace (Fightaging)

Certain forms of mitochondrial DNA damage are one of the causes of aging. Your mitochondria, the cell’s power plants, are the remnants of ancient symbiotic bacteria. Most of their original DNA is lost or migrated to the cell nucleus, but a small number of genes remain. This DNA is much more vulnerable to damage and has worse repair mechanisms than nuclear DNA, but if important parts are lost then the outcome can be dysfunctional mitochondria that overtake the cell because they are more resistant to being cleared out by quality control mechanisms. That cell will then cause harm to surrounding…